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Progesterone: What is it ?

First of all its a hormone that has been around for about 500 million years. That makes it the oldest hormone!

Why is this important?

Because it shows how vital it is to the lives of a great many creatures on the planet.

It is essential to all vertebrates: fishes, reptiles, birds and mammals – including humans. It has countless functions in both sexes and all ages – regulating blood sugar, developing intelligence, building bones, brain activity and many more.

Natural” progesterone – just as your body makes it – is a unique substance with unique properties that cannot be faked and that are essential to good health and to life itself.

Our bodies make it all the time.


In the higher animals it is involved in reproduction, but not being exclusively a sex hormoneit does not impart any secondary sexual characteristics. It is converted by the adrenal glands into other hormones such as cortisone, estrogen, testosterone and others.

William Allen and George Corner first isolated progesterone in 1934 and proposed the name because of its “progestational” activity in the pregnant female. This was an unfortunate choice of name as it has now come to be regarded as a female sex hormone, and it’s many other roles having been largely forgotten.

It was not until 1943 that Russell Marker made it from the plant steroid diosgenin. Originally he used the Mexican wild yam (dioscorea villosa) as a source plant. However, diosgenin has now been found in many other plants, including the spice fenugreek and the soya bean.

Once it was established that it could be produced like this biochemists began converting it into other hormones. These include cortisone, testosterone, estrogen and of course the“unnatural” progestins or progestogens.



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